Tens of thousands of Londoners died of cholera from the 1830s to the 1860s. The causes were simple: mass quantities of human waste and industrial contaminants were pouring into the Thames, the central waterway of a city at the center of a rapidly industrializing world. The river gave off an odor so rank that Queen Victoria once had to cancel a leisurely boat ride. By the summer of 1858, Parliament couldn’t hold hearings due to the overwhelming stench coming through the windows.

What does it mean that one of my favorite demos at CES 2019 — the world’s foremost technology show — was a block of wood? Maybe that I’ve been spending too much time in my garage with a table saw. Maybe that we’re collectively suffering from a bad case of screen fatigue. Maybe both. But if the crowd surrounding Mui is any indication, I’m not the only one smitten with the Kyoto-based company’s head-smackingly simple approach to technology.

Commentary: I haven't eaten beef in a decade, and the new fake meat at CES comes close enough to cow to gross me out. That's a compliment, I think.

Far from Apple’s troubles in emerging markets and China, the company is attracting the ire of what should really be a core supporter demographic naturally aligned with the pro-privacy stance CEO Tim Cook has made into his public soapbox in recent years — but which is instead crying foul…

I learned this in a newsletter from the Secular Coalition for America (SCA) that raised an alarm about the recent success of the Religious Right in getting the current U.S. administration to pack Supreme Court and federal court benches with uber-conservative jurists who embrace “a twisted definition of religious liberty.”

Bethesda parent company ZeniMax has filed a trademark application for a new game called "Deathloop." The goods and services description in the trademark application filed with the United States Patent & Trademark Office on December 26, 2018 states that Deathloop could be an online-enabled mobile game. That's all there is to go on at this stage, however. Trademark applications are not necessarily good predictors of future products, but they're still intriguing to look over...

Tesla knocked $2,000 off of the prices of its cars in the US on Wednesday to help offset a recent reduction of the federal electric vehicle tax credit. The automaker also announced initial delivery and production numbers for the fourth quarter of 2018, showing that the frenzied pace it carried through most of the year — led by the big Model 3 push — helped Tesla set new company records, even though it cooled toward the end.

Many transgenic mouse models exist that mimic a range of Alzheimer’s disease (AD)—related pathologies. They play a key role in both basic research and preclinical testing of potential therapeutics for AD. Although they have contributed greatly to the pathophysiology of β-amyloid toxicity, none fully replicates the human disease.

When LeBron James bounds down a basketball court, he is both a transcendent athlete and a prominent palette for dozens of tattoos. His mother’s name, Gloria, rests on a crown on his right shoulder and his forearms bear a portrait of his son LeBron Jr. and 330, an area code for his hometown, Akron, Ohio. Although those tattoos have personal connections, they may not truly be his.

Our collective overuse and misuse of antibiotics is accelerating resistance to these universal drugs, leaving people increasingly vulnerable to infections that can no longer be treated. This applies not only to the use of antibiotics in human medicine, but also in animal industries. Antibiotic resistance is an example of a collective action problem. These are problems where what is individually rational leads to a collectively undesirable outcome.

A measure of U.S. consumer confidence posted its sharpest decline in more than three years in December, rattling investors already nervous about the prospect that a global economic slowdown was spilling over into the United States. In a sign households were growing more worried about the economy, the Conference Board on Thursday said its consumer confidence index fell this month by 8.3 points to a reading of 136.4, the largest one-month drop since July 2015.

Former longtime CBS News anchor Dan Rather on Tuesday knocked President Trump after the president's Christmas Eve phone call with a 7-year-old went viral due to Trump asking a 7-year-old girl if she believed in Santa Claus. Rather used Trump's language from the call in which the president asked if it was "marginal" for a 7-yeard-old to believe in Santa.

Have you ever played a game for hours or days, only to find a technique, weapon or option tucked away in a labyrinthine menu that radically changes how you play the game, or makes it instantly easier? It can be a welcome feeling, realizing that a difficult task is now made trivial. But it can be equally infuriating, knowing that the hours behind you have been ground out doing unnecessary work.

You wouldn’t be worried if a cat was stuck at the roof of a house because they have a nice grip and they can handle themselves and rescuing them, with their small size of a body wouldn’t cause much trouble. But what do you when a 10-year-old husky is stuck on the roof? Captain Jeff Nawfel, a firefighter, was in a similar dilemma recently.

zritic is now level 36 with 4,535,580 XP.

The worst mass extinction in known history happened 250 million years ago, wiping out an astonishing 96% of all marine life. Scientists have offered many theories on how this could have happened, from meteors to volcanoes–but a research team may have finally cracked the code, and it doesn’t bode well for our own future. Charlie brings in a paper that takes a grim dive into the world’s most lethal time period.