A Deceptively Simple Tweak to CRISPR Makes It 50 Times More Accurate
CRISPR may be the premiere gene editing progeny poised to upend natural genomes and erase inherited diseases. But since its inception, one thing has always stood in the way: accuracy. Back in 2017, a contentious report using CRISPR found massive off-target edits in mice, in which the tool went rogue to snip away at innocent genes.
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