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+19 +6
Biomarkers in fathers’ sperm linked to offspring autism
Biomarkers in human sperm have been identified that can indicate a propensity to father children with autism spectrum disorder. These biomarkers are epigenetic, meaning they involve changes to molecular factors that regulate genome activity such as gene expression independent of DNA sequence, and can be passed down to future generations.
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+23 +5
Now We Know Why Platypus Are So Weird - Their Genes Are Part Bird, Reptile, And Mammal
The first complete map of a platypus genome has just been released, and it's every bit as strange as you'd expect from a creature with 10 sex chromosomes, a pair of venomous spurs, a coat of fluorescent fur, and skin that 'sweats' milk.
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+12 +2
30 Years Since the Human Genome Project Began, What’s Next?
Eric Green, head of the nation’s top genomics research institute, looks back on how far the field has come and shares his bold vision for the future.
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+22 +4
Researchers restore lost sight in mice, offering clues to reversing aging
But many hurdles remain before approach can be tried in people
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+13 +1
The Epigenetic Secrets Behind Dopamine, Drug Addiction and Depression
New research links serotonin and dopamine not just to addiction and depression, but to the ability to control genes.
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+18 +3
A potential new treatment for premature aging diseases keeps stem cells fresh longer
The ends of our DNA, called telomeres, get shorter as we age. Our cells lose a bit of telomere every time they divide. This shortening is a normal and needed process that serves a protective function against cancer. This is because the older our cells get, the more likely they are to have accumulated damage or mutations that make them function incorrectly. Telomere shortening helps to take old cells that are reaching their “best before date” off the shelf before they can cause trouble.
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+10 +2
The curious DNA circles that make treating cancer so hard
Scientists are examining long-ignored extrachromosomal DNA to understand how cancer evolves resistance to drugs. Can the clues help us outfox cancer itself?
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+12 +1
We discovered a missing gene fragment that's shedding new light on how males develop
A new finding in mice rewrites the textbook explanation of the male sex-determining gene, Sry. It might also help us better understand how males and females come to be.
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+13 +2
Genetics Steps In to Help Tell the Story of Human Origins
It’s not unusual for geochronologist Rainer Grün to bring human bones back with him when he returns home to Australia from excursions in Europe or Asia. Jawbones from extinct hominins in Indonesia, Neanderthal teeth from Israel, and ancient human finger bones unearthed in Saudi Arabia have all at one point spent time in his lab at Australian National University before being returned home.
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+23 +4
In a first, a person’s immune system fought HIV — and won
Some rare people may purge most HIV from their bodies, leaving only broken copies of the virus or copies locked in molecular prisons, from which there is no escape.
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+14 +1
DNA from an ancient, unidentified ancestor was passed down to humans living today
A new analysis of ancient genomes suggests that different branches of the human family tree interbred multiple times, and that some humans carry DNA from an archaic, unknown ancestor. Melissa Hubisz and Amy Williams of Cornell University and Adam Siepel of Cold Spring Harbor Laboratory report these findings in a study published 6th August in PLOS Genetics.
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+3 +1
Small Protein, Big Breakthrough for CRISPR Gene Editing
A new protein opens doors for gene editing by gaining access to hard-to-reach areas of the genome.
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+3 +1
African American Genomes Yield Insight into Slavery Practices
A massive study finds that regional differences in how slaves were treated throughout the Americas are reflected in the DNA of present-day Americans of African descent.
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+12 +2
Neandertals may have had a lower threshold for pain
Pain is mediated through specialized nerve cells that are activated when potentially harmful things affect various parts of our bodies. These nerve cells have a special ion channel that has a key role in starting the electrical impulse that signals pain and is sent to the brain. According to a new study by researchers at the Max Planck Institute for Evolutionary Anthropology in Germany and the Karolinska Institutet in Sweden people who inherited the Neandertal variant of this ion channel experience more pain.
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+11 +1
Gedmatch investigating after users DNA profile made available to police
Gedmatch, the DNA analysis site that police used to catch the so-called Golden State Killer, was pulled briefly offline on Sunday while its parent company investigated how its users’ DNA profile data apparently became available to law enforcement searches.
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+19 +2
New CRISPR enzyme mutation proves almost 100 times more precise
The CRISPR-Cas9 gene editing system is an extremely powerful tool, but there are still a few kinks to iron out. One of the main problems is off-target edits, which can have serious consequences. Now, researchers have found a particular mutation of the CRISPR enzyme that’s almost 100 times more precise than the most commonly used one.
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+14 +3
A 26-Year-Old Gave Birth From an Embryo Frozen for 24 Years
Emma Wren Gibson, frozen as an embryo in 1992, was born a few days after Thanksgiving in 2017, more than 25 years later. It’s the longest an embryo is known to have been frozen before being born as baby. In fact, the embryo that became Emma is only a year younger than the woman who gave birth to her, Tina Gibson. “This embryo and I could have been best friends,” Gibson, now 26, told CNN. Tina and her husband “adopted” the frozen embryo after learning he was likely infertile.
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+4 +1
Colonizing Mars may require humanity to tweak its DNA
If humanity is ever going to settle down on Mars, we may need to become a little less human. Crewed missions to Mars, which NASA wants to start flying in the 2030s, will be tough on astronauts, exposing them to high radiation loads, bone-wasting microgravity and other hazards for several years at a time. But these pioneers should still be able to make it back to Earth in relatively good nick, agency officials have said.
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+13 +2
Scientists grow mouse which is 4% human
Researchers have created an embryo containing both human and mouse cells in a major advancement of genetically modified organisms. The hybrid embryo, referred to as a human-animal chimera, was grown by a team at the State University of New York at Buffalo and the Roswell Park Comprehensive Cancer Center.
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+17 +2
The secret to why some people get so sick from covid could lie in their genes
Some people die from covid-19, and others who are infected don’t even show symptoms. But scientists still don’t know why. Now consumer genomics company 23andMe is going to offer free genetic tests to 10,000 people who’ve been hospitalized with the disease, hoping to turn up genetic factors that could point to an answer.
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