At Imperial College we’ve been comparing psilocybin to conventional antidepressants – and the results are likely to be game-changing, says Robin Carhart-Harris

Do antidepressants work? If so, which antidepressants are most effective? These two questions have been posed again and again over the last few decades, but the answer has remained elusive. The latest answer to the question of which antidepressants are most effective and well-tolerated comes from a 2018 paper. Published in The Lancet, the paper reported the results of the largest meta-analysis conducted to date on the acceptability and efficacy of 21 antidepressant treatments

Self‐reported sleep patterns and quality amongst adolescents: cross‐sectional and prospective associations with anxiety and depression. A mere 30 minutes extra sleep a day can make all the difference to a teenager’s lifelong mental health and wellbeing. A new international study of almost 5000 adolescents found those who generally slept 30 minutes less per night reported feeling anxious or depressed compared to other groups.

Once more, with feeling.

Facebook is designed to make you anxious, depressed and dissatisfied, three states of mind that make you more vulnerable to advertising and other forms of behavioral manipulation. Small wonder, the…

Scientists have taken a small step toward personalizing treatment for depression. A study of more than 300 people with major depression found that brain wave patterns predicted which ones were most likely to respond to the drug sertraline (Zoloft), a team reported Monday in the journal Nature Biotechnology.

EEGs successfully picked out which depressed individuals got better on the drug Zoloft

Too much time sitting still – sedentary behaviour – is linked to an increased risk of depressive symptoms in adolescents, finds a new UCL-led study.

As we all know, unless you can afford a medical concierge and the most expensive insurance and facilities, the for-profit, private-insurance-based health care system in the United States is somewhere between a headache and a nightmare. Inpatient mental health care is no exception. The quality of life is ultimately defined by your insurance company’s concern to avoid liability.

Workers who omit breakfast show a heightened risk of depressive symptoms, according to a study published in Psychiatry Research.

Stanford Medicine researchers used high doses of magnetic stimulation, delivered on an accelerated timeline and targeted to individual neurocircuitry, to treat patients with severe depression.

Mood varies from hour-to-hour, day-to-day and healthy mood regulation involves choosing activities that help settle one’s mood. However, in situations where personal choices of activities are constrained, such as during periods of social isolation and lockdown, this natural mood regulation is impaired which might result in depression. New research, published today in JAMA Psychiatry, from the Department of Psychiatry, University of Oxford suggests a new target for treating and reducing depression is supporting natural mood regulation.

Risks for autism and depression are higher if one’s mother was in hospital with an infection during pregnancy. This is shown by a major Swedish observational study of nearly 1.8 million children.

Field Trip's first location is based in downtown Toronto. Two new locations in Los Angeles and New York will open later this summer.

Even before the COVID pandemic, many experts posited that loneliness was itself an American epidemic. Now, many fear the reduction in social contact may especially affect those populations most vulnerable to isolation and loneliness. Now, emerging research explores the manner in which the brain maps relationships with other people in relation to one’s self.

Some people have a legitimate reason to feel depressed, but not me. I just woke up one day feeling sad and helpless for absolutely no reason.

On Monday, August 11, 2014, the world lost a great man. Robin Williams was found unresponsive in his home and it was suspected to be a suicide via asphyxiation.

You own a home, have a family, and are generally happy but have been feeling “off” lately. You work hard, you are feeling more tired than usual, and don’t know why. One day, you return from work and sit down to watch some television to unwind from your hard day. Your family hasn’t come home yet so you head to the kitchen to fix yourself a PB & J sandwich to tie yourself over until supper.

Last November, my father took his own life. I'm frequently aware of the fact that the depression which helped drive him to that dark fate lives on in my genes. That's a doozy of a legacy to inherit, but it's one that has not been wholly negative for me.

There are many faces to depression: sadness, hopelessness, trouble sleeping, lack of motivation, an inability to experience pleasure. That last one has a medical name—anhedonia—and people experiencing it often no longer enjoy activities that used to bring happiness. Anhedonia is not found just in depression; it can be an important part of other disorders, including schizophrenia, obsessive-compulsive disorder and addiction.