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It can begin with abdominal pressure from a bloating belly. This can escalate into cramping pain and nausea. Or, a sudden urge to flee to the toilet right now.
This was interesting. I got IBS after my fifth bout of food poisoning when my colon threw in the towel and said:I can't work like this,I'll be in my trailer!"
From my reading (and occasional experience) first generation antihistamines do the trick.
The down side is they are antiallergics,which have nasty side effects,so I use Holigos.