Immune cells boost cancer survival from months to years
When immunologist Michel Sadelain launched his first trial of genetically engineered, cancer-fighting T cells in 2007, he struggled to find patients willing to participate. Studies in mice suggested that the approach — isolating and engineering some of a patient’s T cells to recognize cancer and then injecting them back — could work. But Sadelain did not blame colleagues for refusing to refer patients. “It does sound like science fiction,” he says. “I’ve been thinking about this for 25 years...
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