A Phase 3 trial for Northwest Biotherapeutics’s DCVax-L vaccine extended survival in patients with gliobastoma for many months, or in some cases, years: according to new data.

Past studies have used the gene-editing technology CRISPR to remove genes from immune system cells to make them better at fighting cancer. Now, PACT Pharma and UCLA have used CRISPR to remove and add genes to these cells to help them recognize a patient’s specific tumor cells.

An experimental therapeutic cancer vaccine induced two distinct and desirable immune system responses that led to significant tumor regression in mice, report investigators from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

Found naturally only in a single rainforest tree species, the compound can now have expanded availability for research and clinical uses.

Engineers at Duke University have developed a novel delivery system for cancer treatment and demonstrated its potential against one of the disease’s most troublesome forms. In newly published research in mice with pancreatic cancer, the scientists showed how a radioactive implant could completely eliminate tumors in the majority of the rodents, demonstrating what they say is the most effective treatment ever studied in these pre-clinical models.

Uğur Şahin and Özlem Türeci say mRNA Covid vaccine technology could be repurposed to help destroy cancer cells.

Scientists are working on vaccines that train cells to see tumors as foreign, in hopes of one day making breast cancer preventable.

Genetically engineering viruses to create an injection that can treat cancer is the aim currently being pursued by a number of different laboratories around the world.

A study of genetic test results used to guide cancer treatment found that Black people had their tumours misclassified twice as often as white people

A new type of cancer therapy that uses a common virus to infect and destroy harmful cells is showing big promise in early human trials, say UK scientists. One patient's cancer vanished, while others saw their tumours shrink. The drug is a weakened form of the cold sore virus - herpes simplex - that has been modified to kill tumours.

Chemotherapy drugs can be lifesaving – but they don’t work for all patients or for all cancers. That’s why a team of researchers at the University of Toronto Mississauga is looking at new ways to use special types of light to target cancer cells resistant to current drug therapy – an approach that might be easier on some patients than traditional chemotherapy.

Tumor cells are notoriously good at evading the human immune system; they put up physical walls, wear disguises and handcuff the immune system with molecular tricks. Now, UC San Francisco researchers have developed a drug that overcomes some of these barriers, marking cancer cells for destruction by the immune system.

Doctors hail new era for cancer screening as major research shows effectiveness of Galleri test

A tiny group of people with rectal cancer just experienced something of a scientific miracle: their cancer simply vanished after an experimental treatment. In a very small trial done by doctors at New York's Memorial Sloan Kettering Cancer Center, patients took a drug called dostarlimab for six months. The trial resulted in every single one of their tumors disappearing. The trial group included just 18 people, and there's still more to be learned about how the treatment worked. But some scientists say these kinds of results have never been seen in the history of cancer research.

The study found vitamin D keeps cancer cells from transforming mesothelial cells, or those found outside organs, into less protective versions.

Phase I study shows that mRNA-based vaccines can be used to stimulate T cells to recognise neoantigens in pancreatic cancer patients.

A small group of people with rectal cancer just experienced something of a miracle as their cancer simply vanished after an experimental treatment.

Researchers found that subjects who underwent weight loss surgery also showed a sharp decrease in their likelihood of dying from cancer.

A new gene therapy shrank the tumors of a woman with pancreatic cancer. Researchers think it has the potential to benefit millions more people.

A new study published in Frontiers in Aging found that a combination of high-dose vitamin D, omega-3s, and a simple home strength exercise program (SHEP) showed a cumulative reduction by 61% in cancer risk in healthy adults aged 70 or older. It is the first study to test the combined benefit of three affordable public health interventions for the prevention of invasive cancers. Following future studies, the results may impact the future of cancer prevention in older adults.