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+20 +1
Body fat transformed by CRISPR gene editing helps mice keep weight off
CRISPR gene editing can turn white fat cells into brown fat that burns energy, a technique that limited weight gain in mice and could potentially be used to treat obesity-related disorders
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+3 +1
Small Protein, Big Breakthrough for CRISPR Gene Editing
A new protein opens doors for gene editing by gaining access to hard-to-reach areas of the genome.
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+11 +1
Scientists accidentally create the "sturddlefish" — a new fish hybrid from two endangered species
Meet the sturddlefish: a new species of fish accidentally created by scientists in Hungary. It's an unusual mix of two endangered species, the American Paddlefish and the Russian Sturgeon. According to a study published in the journal Genes, researchers at Hungary's National Agricultural Research and Innovation Centre, Research Institute for Fisheries and Aquaculture said that they were not trying to create a new fish when the sturddlefish was born. Rather, they just wanted to know if the two species could be bred in captivity — and were shocked when the resulting fish actually grew to adulthood.
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+19 +1
New CRISPR enzyme mutation proves almost 100 times more precise
The CRISPR-Cas9 gene editing system is an extremely powerful tool, but there are still a few kinks to iron out. One of the main problems is off-target edits, which can have serious consequences. Now, researchers have found a particular mutation of the CRISPR enzyme that’s almost 100 times more precise than the most commonly used one.
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+16 +1
Three people with inherited diseases successfully treated with CRISPR
Two people with beta thalassaemia and one with sickle cell disease no longer require blood transfusions, which are normally used to treat severe forms of these inherited diseases, after their bone marrow stem cells were gene-edited with CRISPR.
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+2 +1
Capabilities of CRISPR gene editing expanded
Many basic and clinical researchers are testing the potential of a simple and efficient gene editing approach to study and correct disease-causing mutations for conditions ranging from blindness to cancer, but the technology is constrained by a requirement that a certain short DNA sequence be present at the gene editing site.
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+20 +1
$100 Genome Sequencing Will Yield a Treasure Trove of Genetic Data—and Maybe a Dystopian Nightmare
What would the implications be if decoding your genes cost less than a pair of designer jeans? We might soon find out after a Chinese company claimed it can sequence the human genome for $100. The speed at which the price of genetic sequencing has fallen has been astonishing, from $50,000 a decade ago to roughly $600 today. For a long time, the industry saw the $1,000 genome as the inflection point at which we would enter the genomic age—where getting a read out of your DNA would be within reach for huge swathes of the population.
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+10 +1
Doctors use CRISPR gene editing inside a person's body for first time
The tool was used in an attempt to treat a patient's blindness. It may take up to a month to see if it worked.
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+30 +1
CRISPR was just used in a bid to restore sight to a blind person
The gene-editing tool CRISPR has been used for the first time inside the body of an adult patient, in an attempt to cure a form of blindness. The treatment: According to the Associated Press, doctors dripped just a few drops of a gene-editing mixture beneath the retina of a patient in Oregon who suffers from Leber congenital amaurosis, a rare inherited disease that leads to progressive vision loss.
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+24 +1
Why Bill Gates thinks gene editing and artificial intelligence could save the world
Microsoft co-founder Bill Gates has been working to improve the state of global health through his nonprofit foundation for 20 years, and today he told the nation’s premier scientific gathering that advances in artificial intelligence and gene editing could accelerate those improvements exponentially in the years ahead.
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+2 +1
Human trial suggests CRISPR could be a viable cancer treatment
Scientists from the University of Pennsylvania just published the results of the first U.S. trial of CRISPR-edited cells in cancer patients — and they’re very encouraging. In April 2019, UPenn confirmed that a team of its researchers had officially begun testing CRISPR-edited cells in humans.
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+4 +1
First Human Clinical Trial Finds CRISPR Gene-edited Cells Safe and Durable for Cancer Therapy
Scientists report positive safety and durability results from the first U.S. test of CRISPR gene editing in human patients with advanced cancer. Technology Networks spoke to the researchers to find out more.
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+16 +1
CRISPR gene-editing corrects muscular dystrophy in pigs
Duchenne muscular dystrophy (DMD) is one of the most common and most devastating muscular diseases, greatly reducing patients’ quality of life and life expectancy. Now, researchers in Germany have managed to use the CRISPR gene-editing tool to correct the condition in pigs, bringing the treatment ever closer to human trials.
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+19 +1
A scientist who genetically edited babies to be HIV-resistant was just sentenced to 3 years in prison. Here's how he did it and why scientists around the world are outraged.
He Jiankui, the scientist in China who shocked the world in 2018 when he claimed responsibility for the births of the first two genetically edited babies, has been sentenced to three years in prison, according to Chinese state media reports on Monday.
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+28 +1
The first U.S. trials in people put CRISPR to the test in 2019
When it was unveiled in 2012, people had great hopes that the gene editor CRISPR/Cas9 could treat or even cure hundreds to thousands of genetic diseases. This year, researchers in the United States began testing the gene editor in people, a crucial first step in determining whether the technology can fulfill its medical promise.
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+17 +1
Monkey-pig hybrids created by Chinese scientists
Chinese scientists have successfully bred monkey-pig hybrids as part of research into the growth of human organs for transplantation in animals. Although the two chimera piglets died within a week of being born, both were found to have DNA from macaque monkeys in their heart, liver, spleen, lung and skin. They were bred from more than 4,000 embryos which were implanted into a sow using IVF, according to the New Scientist.
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+22 +1
Gene editing will let us control our very evolution. Will we use it wisely?
We live in a time when science and technology are having an impact on our society in more and more ways. And the decisions that shape how these new fields of knowledge develop ultimately affect all of us.
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+4 +1
CRISPR Approach To Fighting Cancer Called 'Promising' In 1st Safety Test
Attempts to use the gene-editing tool CRISPR to develop a treatment for cancer seem safe and feasible in the earliest findings from the first three patients. "So far, so good," scientists say.
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+16 +1
CRISPR used to edit rice DNA as defense against pathogen
Altering rice genes the pathogen needs renders rice strains resistant to blight.
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+18 +1
A New Crispr Technique Could Fix Almost All Genetic Diseases
Andrew Anzalone was restless. It was late fall of 2017. The year was winding down, and so was his MD/PhD program at Columbia. Trying to figure out what was next in his life, he’d taken to long walks in the leaf-strewn West Village. One night as he paced up Hudson Street, his stomach filled with La Colombe coffee and his mind with Crispr gene editing papers, an idea began to bubble through the caffeine brume inside his brain.
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