Killing Resistant Superbugs with Antibiotic Triumvirate
The exponential rise in antibiotic-resistant microbes is a major public health threat worldwide. Moreover, with approval times for new antibiotics taking more than a decade in most cases, finding a viable treatment among previously approved compounds is imperative to stem the drug-resistant tide. Now, investigators at the University at Buffalo (UB) have encouraging new data on a trio of antibiotics that when used in concert together, are capable of eradicating deadly Escherichia coli carrying the mcr-1 and ndm-5 genes—making the bacterium immune to last-resort antibiotics.
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