Gene Linked to Impaired Memory in Down Syndrome – A Potential Drug Target?
It may one day be possible to reverse abnormal embryonic brain development linked to Down syndrome (DS) and improve cognitive function by therapeutically targeting a key gene known as OLIG2 prenatally, suggests newly published findings. The study published in Cell Stem Cell sought to understand the mechanisms underlying imbalances in excitatory and inhibitory neurotransmission that may be responsible for cognitive defects in DS patients.
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