Anything by Yoshitoshi ABe is unique (Lain, Texhnolyze, Haibane Renmei)
Kaiji and Akagi have quite unique art styles (and some of the best noses you'll ever see)
Yuasa Masaaki always does something unique (Kaiba, Tatami Galaxy, Ping Pong)
Mononoke
Redline - some of the best animations currently
Kuuchuu Buranko
Aku no Hana - looks ugly at first but you get used to it, fits the show
PSG - Gainax doing American cartoon style, dub is infinitely better
Anything by Yoshitoshi ABe is unique (Lain, Texhnolyze, Haibane Renmei)
Kaiji and Akagi have quite unique art styles (and some of the best noses you'll ever see)
Yuasa Masaaki always does something unique (Kaiba, Tatami Galaxy, Ping Pong)
Mononoke
Redline - some of the best animations currently
Kuuchuu Buranko
Aku no Hana - looks ugly at first but you get used to it, fits the show
PSG - Gainax doing American cartoon style, dub is infinitely better