Depriving Deadly Brain Tumors of Cholesterol May Be Their Achilles’ Heel
Researchers at University of California San Diego School of Medicine, Ludwig Institute for Cancer Research and The Scripps Research Institute, with colleagues in Los Angeles and Japan, report that depriving deadly brain cancer cells of cholesterol, which they import from neighboring healthy cells, specifically kills tumor cells and caused tumor regression and prolonged survival in mouse models. The findings, published in the online October 13 issue of Cancer Cell, also present a potential alternative method for treating glioblastomas...
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