Vaccines against SARS-CoV-2 are based on a range of novel vaccine platforms, with adenovirus-based approaches (like ChAdOx1 nCov-19) being one of them. Recently a rare and novel complication of SARS-CoV-2 targeted adenovirus vaccines has emerged: thrombosis with thrombocytopenia syndrome (TTS). TTS is characterized by low platelet counts, clot formation at unusual anatomic sites and platelet-activating PF4-polyanion antibodies reminiscent of heparin-induced thrombocytopenia. Here, we employ in vitro and in vivo models to characterize the possible mechanisms of this platelet-targeted autoimmunity.

As the coronavirus spiked in Missouri last fall, a wave of cases hit a nursing home in the state’s rural heartland. Robin Bull, a part-time nurse, remembered an ambulance “coming and going constantly” on one especially scary morning, rushing residents to Moberly Regional Medical Center, the local hospital.

A first-in-human, Phase 1 trial assessing the safety and immunogenicity of an investigational nanoparticle influenza vaccine designed to provide long-lasting protection against multiple flu virus strains has begun at the National Institutes of Health Clinical Center in Bethesda, Maryland. Healthy participants 18 to 50 years old will receive either a licensed seasonal influenza vaccine or the experimental vaccine, FluMos-v1. Scientists from NIH's National Institute of Allergy and Infectious Diseases (NIAID) developed FluMos-v1 to stimulate antibodies against multiple influenza virus strains by displaying part of the influenza virus...

A remarkable, yet potentially fraught treatment for people who, in the past, have been diagnosed with schizophrenia.

A Future of Medicine - a discussion on the current state of clinical trials

The vaccine for human papillomavirus (HPV) is recommended in the United States for all young people up to age 26 to help prevent certain deadly cancers.

A Scottish doctor is widely credited with inventing the hypodermic syringe - a crucial tool in the battle against Covid.

We've all done it. Maybe you have a weird rash, or a cough that just won't go away, so you turn to Google to look up your symptoms.

A review of paracetamol for 44 common pain conditions found no strong evidence to support its use in many instances. Paracetamol is also known as acetaminophen, Panadol, Tylenol.

Doctors should hold off clamping the umbilical cords for premature babies to help give them the best chance to thrive in their critical first days of life, a major investigation shows.

People are trying to treat and prevent COVID-19 by taking ivermectin, a medication commonly used to de-worm horses – and they are poisoning themselves in the process.

A family doctor's recommendation to follow a whole foods, plant-based diet coincided with a life-changing turnaround in the fortunes of one patient – potentially triggering complete recovery from a mysterious and painful disease.

After waking up and spending an hour shovelling snow, Massachusetts man Brad Gauthier realises something is wrong when he can't swallow a glass of water.

This definitive guide will explain the difference between an HDHP vs PPO plan, how much they cost, and which one you should choose for your family.

A study of 45 countries shows those who have contained the virus also tend to have less severe economic impacts than those which haven’t

Los Angeles County’s healthcare system was buckling Wednesday under the unprecedented surge of covid-19 patients, with bodies piling up at morgues and medical professionals resorting to increasingly desperate measures as they brace for conditions to worsen in the coming weeks. With hospitals overwhelmed by patients and no outlet valve available,

Scientists in the UK have just recruited the first participants in the world to be part of a new long-acting antibody study.

The recovery from the most traumatic global economic catastrophe since the Great Depression will be far from equal.

Whether randomized controlled trials of niche medicines can work

Why is a group of prestigious doctors and scientists who have the backing of the most profitable industry in the world according to Fortune 500 – the pharmaceutical industry – targeting a few poorly-funded natural medicine courses?