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+16 +1
CRISPR and another genetic strategy fix cell defects in two common blood disorders
It is a double milestone: new evidence that cures are possible for many people born with sickle cell disease and another serious blood disorder, beta-thalassemia, and a first for the genome editor CRISPR.
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+10 +1
1st Patients To Get CRISPR Gene-Editing Treatment Continue To Thrive
The last thing a lot of people want to do these days is get on a plane. But even a pandemic would not stop Victoria Gray. She jumped at the chance to head to the airport this summer. "It was one of those things I was waiting to get a chance to do," says Gray. She had never flown before because she was born with sickle cell disease. She feared the altitude change might trigger one of the worst complications of the devastating genetic disease — a sudden attack of excruciating pain.
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+3 +1
Humans will be able to live forever
Some believe that soon humans will be able to live 1,000 years. We will continue to die, but instead of dying in the hospital while all our organs fail at the age of 90, we could spend a thousand years surrounded by the people we love, enjoying life. The basic idea behind biological aging is that aging occurs as you gradually accumulate damage to various cells and tissues in the body.
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+16 +1
Personalized Skin Cancer Vaccine Shows Promise in New Trial Results
The future of cancer treatment might involve personalized vaccines meant to manage or even prevent relapses—at least if new research published Thursday continues to pan out. In a small clinical trial, high-risk melanoma patients given such a vaccine were able to create a long term, durable immune response to their cancer, scientists said. They also remained alive four years after the initial treatment, with most being actively disease-free.
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+12 +1
A Single Shot Restored Vision to a Blind Child for an Entire Year
A patient suffering from a genetic form of childhood blindness regained and retained vision for more than a year after receiving just a single shot of an experimental RNA therapy directly into the eye, according to a new study published in the journal Nature Medicine.
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+26 +1
A Massive New Gene Editing Project Is Out to Crush Alzheimer’s
When it comes to Alzheimer’s versus science, science is on the losing side. Alzheimer’s is cruel in the most insidious way. The disorder creeps up in some aging brains, gradually eating away at their ability to think and reason, whittling down its grasp on memories and reality. As the world’s population ages, Alzheimer’s is rearing its ugly head at a shocking rate. And despite decades of research, we have no treatment—not to mention a cure.
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+15 +1
The good, the bad and the truly horrifying potential of CRISPR technology
This remarkable technology has the potential to eliminate all genetic disorders and is already delivering results that scientists say were unimaginable just a few years ago.
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+20 +1
A New CRISPR Tool Flips Genes On and Off Like a Light Switch
CRISPRoff can cause a gene to stay silent for hundreds of generations, even when its host cells morph from stem cells into more mature cells.
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+21 +1
A New Gene Editing Tool Could Rival CRISPR, and Makes Millions of Edits at Once
With CRISPR’s meteoric rise as a gene editing marvel, it’s easy to forget its lowly origins: it was first discovered as a quirk of the bacterial immune system.
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+14 +1
Breakthrough CRISPR Gene Therapy Could Be a 'One and Done' Injection
In an early trial, patients received a single infusion of a CRISPR-based therapy to knock out the mutated gene responsible for their disease.
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+20 +1
Landmark CRISPR trial shows promise against deadly disease
Preliminary results from a landmark clinical trial suggest that CRISPR–Cas9 gene editing can be deployed directly into the body to treat disease. The study is the first to show that the technique can be safe and effective if the CRISPR–Cas9 components — in this case targeting a protein that is made mainly in the liver — are infused into the bloodstream.
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+16 +1
CRISPR stops coronavirus replication in human cells
Scientists have harnessed CRISPR gene-editing technology to block the replication of the novel coronavirus in human cells — an approach that could one day serve as a new treatment for COVID-19.
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+19 +1
World's Leading Geneticists Aim to Resurrect Woolly Mammoth
It was a member of a small, isolated community of mammoths that was the last vestige of a once-thriving species that could be found roaming the plains of the northern hemisphere from Alaska to Siberia. Scientists still debate what caused the mammoths to finally go extinct, but the general consensus is that it was a combination of human hunting, genetic defects from inbreeding, and natural climate change, which shrank suitable mammoth habitat by a factor of ten.
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+19 +1
This startup is going to resurrect the mammoth through CRISPR
You’ve heard of startups building computer chips, delivery drones and social networks. One called Colossal has a very different goal: bringing the woolly mammoth back from extinction by 2027 using CRISPR, a revolutionary gene editing technology. Colossal’s co-founders are Chief Executive Ben Lamm, who started five companies before this, and George Church, a Harvard Medical School professor with deep CRISPR expertise.
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+18 +1
CRISPR-based 'antibiotic' eliminates dangerous bacterium from the gut
Genetically engineered bacteria armed with CRISPR could help combat antibiotic-resistant infections and also allow doctors to edit people's microbiomes
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+23 +1
CRISPR gene therapy, ultrasound and drugs team up against liver cancer
Researchers in China have developed a new three-pronged method to fight liver cancer that shows promise in tests in mice. The technique combines drugs and CRISPR-Cas9 gene editing into lipid nanoparticles, then activates them with ultrasound.
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+7 +1
The tomatoes at the forefront of a food revolution
As global temperatures increase and extreme weather events become more common, can gene editing help to tweak our food plants so they can cope with the changes?
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+12 +1
First sickle cell patient treated with CRISPR gene-editing still thriving
For more than a year, Victoria Gray's life had been transformed. Gone were the sudden attacks of horrible pain that had tortured her all her life. Gone was the devastating fatigue that had left her helpless to care for herself or her kids. Gone were the nightmarish nights in the emergency room getting blood transfusions and powerful pain medication.
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+12 +1
A newly discovered molecule could lead to a cure for pancreatic cancer
It's the dreaded C-word: Cancer. Some dare not even say it in case it happens to them. Despite many advances in science, we are still at a loss for an effective cure for cancer. Now, a research team led by scientists at Roswell Park Comprehensive Cancer Center may have made a significant breakthrough in treating pancreatic cancer, according to a press release published by the institute on Wednesday.
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+4 +1
New cancer treatment uses body’s cellular waste disposal to flag harmful proteins
Scientists are perfecting a new anti-cancer treatment that exploits the body’s own cellular waste disposal system. Some drugs are already producing promising results, and the number of new medicines is expected to rise in the near future with the opening of a British centre dedicated to using the technique.
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