I mostly use firefox and switch over to chrome when I need to watch those videos that you can click and drag to look around. (Also for when firefox is acting up). I tried opera but didn't like the limited amount of addons it offered. I tried to make chrome my main browser but it just couldn't remember my passwords. It was very buggy back in the day. I was turned off by the whole thing, so I switched back to firefox.
I'd like to try microsoft edge, the new browser microsoft announced. But with the last few versions of IE we've had, I'm not sure if I'll like Edge at all.
Edge is currently very nice but lacks some important parts like addons/extensions (support is coming though) and the password management is a bit odd (comes up in a pop-up, for all passwords). I have no problems seeing it becoming a great browser with a few more iterations and at that point I would probably switch considering how fast and lightweight it is.