In a similar vein, there's also Big Pharma, where instead of surviving on a hostile unknown land you're busy trying to produce the most profitable drugs. Quite complex, but apparently the tutorial eases you into the mechanics.
It's in early Beta at the moment.
I might buy Big Pharma as well, I learned about it after I purchased Factorio. Big Pharma looks interesting because it seems to have a much bigger element of space utilization as well, whereas Factorio gives you basically infinite room (you can make maps that require better space efficiency though.)