Permeability of the blood–brain barrier predicts conversion from optic neuritis to multiple sclerosis
These findings suggest that blood–brain barrier permeability, as measured by magnetic resonance imaging, may provide novel pathological information as a marker of neuroinflammation related to multiple sclerosis, to some extent reflecting cellular permeability of the blood–brain barrier, whereas T2 lesion count may more reflect the length of the subclinical pre-relapse phase.
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