Up to a third of the weight lost while taking weight loss jabs such as Wegovy and Mounjaro includes muscle and bone mass.

Gilead could bring the AIDS pandemic towards an end if the US pharmaceutical giant opens up access to its game-changing new HIV drug, the head of UNAIDS told AFP.

Opioids are the one of the most prescribed pain-relief for people with low back and neck pain. But new research shows they don’t effectively relieve low back or neck pain and can result in worse pain.

Nitazenes were developed as a powerful class of painkiller in the 1950s, but they were abandoned – until now.

It takes forever to get drugs on the market. AI could help speed up the process.

Hundreds of thousands of Britons are taking antidepressants for chronic pain without enough evidence they work, according to a large study. Researchers looked at drugs commonly prescribed by the NHS including amitriptyline, duloxetine, fluoxetine (Prozac), citalopram, paroxetine (Seroxat) and sertraline.

More than a dozen new psychoactive drugs have been detected in 16 countries by an international wastewater surveillance program.

Late last year, one of Dr. Vance Fowler’s patients — a man in his 60s who’d returned to North Carolina from visiting his family in Nepal — died of a bacterial infection. He’d been treated at a top U.S. hospital with access to the strongest antibiotics. But the infection, a drug-resistant strain of E. coli, surged on.

It's called a "liver-chip." Researchers grew human liver cells on a small chip-like device, hoping to use it to predict when a drug might cause liver injury. Not only did it do so — flagging a set of small molecule drugs with known hepatoxicity with 87% specificity — but it also outperformed conventional animal models.

"Truth serum" comes in several forms, including sodium pentothal. Find out how the drugs work to make it more difficult — but not impossible — to lie.

The U.S. Food and Drug Administration (FDA) no longer requires new drugs to be tested in animals before being approved. Thanks to a law passed in December 2022(opens in new tab), the agency now has the option to approve drugs that are tested in only non-animal studies, including those that use lab-grown tissues or computer models, before being tested in clinical trials with humans.

Some health companies' quarterly earnings were boosted by COVID-19 products in the past few years, and most are starting to see a shift away from pandemic profits for 2023. Wells Fargo analyst Mohit Bansal said as much about three companies reporting earnings this week: "COVID is pretty much out of the models. Pfizer (PFE) is probably the only one in our coverage where it is still a significant part of it because it was their biggest business last year."

An Eli Lilly drug if approved for weight loss could become the best-selling drug of all time, but concerns are mounting about who will actually be able to afford it. Experts are confident that the drug, called tirzepatide, will be granted approval by the Food and Drug Administration sometime next year. If that’s the case, it would join two other popular — and expensive — recently approved weight loss drugs on the market, Wegovy and Saxenda, both from the drugmaker Novo Nordisk.

Democrats have sent the legislative text of a sweeping proposal for drug price controls to the U.S. Senate parliamentarian, who may report on Monday whether the provisions qualify for the budget reconciliation process that allows lawmakers to evade a filibuster and pass a bill with a simple majority.

Perrigo Company (PRGO.N) said on Monday its unit HRA Pharma has asked the U.S. Food and Drug Administration (FDA) to approve a daily birth control pill for over-the-counter (OTC) sale, the first such request for this type of contraception. The application from the HRA comes on the back of the U.S. Supreme Court's decision in June to overturn the 1973 Roe v. Wade case that legalized abortion nationwide.

People searching for cheaper alternatives to high priced prescription drugs have a new and perhaps unexpected option. It's an online pharmacy founded by Mark Cuban, a billionaire businessman, Shark Tank star and owner of the Dallas Mavericks. His new direct-to-consumer company, Cost Plus Drugs, offers more than 100 generic medications at discounted prices. He joins Geoff Bennett to discuss.

A drug approved to treat Type 2 diabetes is extremely effective at reducing obesity, according to a new study. The drug, called tirzepatide, works on two naturally occurring hormones that help control blood sugar and are involved in sending fullness signals from the gut to the brain.

US pharmaceutical firm Pfizer said it would sell its patented drugs at cost to 45 low-income countries.

After graduating from Columbia University with a chemical engineering degree, my grandfather went on to work for Pfizer for almost two decades, culminating his career as the company’s Global Director of New Products. I was rather proud of this fact growing up — it felt as if this father figure, who raised me for several years during my childhood, had somehow played a role in saving lives.

US drug company Pfizer has penned a deal to allow its experimental Covid-19 treatment pill to be made and sold in 95 developing nations. The deal with the UN-backed Medicines Patent Pool not-for-profit could make the treatment available to 53% of the world's population. But it excludes several countries that have had large Covid-19 outbreaks, including Brazil.