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+23 +1
In a first, a person’s immune system fought HIV — and won
Some rare people may purge most HIV from their bodies, leaving only broken copies of the virus or copies locked in molecular prisons, from which there is no escape.
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+18 +1
Oldest 'nearly complete' HIV genome found in forgotten tissue sample from 1966
The oldest known nearly complete gene sequence from the HIV strain that spread across the world has been found in a tissue sample from the Democratic Republic of the Congo (DRC), a new study finds. The tissue sample was taken and preserved in 1966, making this HIV sequence 10 years older than the previous oldest genome, which came from a blood sample taken in 1976 in the DRC. Gene sequences like these – which come from before the virus that causes AIDS was discovered in 1983 – help pinpoint the timing of genetic mutations in the virus.
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+16 +1
Could the porn industry offer a model for reopening amid Covid-19?
Reopening the economy will involve coronavirus-testing programs and contact tracing similar to those used in the adult film industry for HIV.
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+3 +1
An HIV drug failed to help patients with severe cases of COVID-19, according to disappointing results from one of the first coronavirus drug trials
A potential coronavirus treatment has failed in a randomized clinical trial in China. A group of Chinese researchers tested the HIV drug Kaletra in a group of patients with severe cases of COVID-19, the disease caused by the novel coronavirus. Study results were published Wednesday in The New England Journal of Medicine.
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+20 +1
Second patient cured of HIV, say doctors
Adam Castillejo, the "London Patient", is free of the virus more than 30 months after stopping treatment.
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+17 +1
Another HIV vaccine strategy fails in large-scale study
A trial in South Africa was halted after early analysis found no protection
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+4 +1
Imaging study of key viral structure shows how HIV drugs work at atomic level
Salk scientists have discovered how a powerful class of HIV drugs binds to a key piece of HIV machinery. By solving, for the first time, three-dimensional structures of this complex while different drugs were attached, the researchers showed what makes the therapy so potent. The work, which appeared in Science on January 30, 2020, provides insights that could help design or improve new treatments for HIV.
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+3 +1
H.I.V. Is Reported Cured in a Second Patient, a Milestone in the Global AIDS Epidemic
Scientists have long tried to duplicate the procedure that led to the first long-term remission 12 years ago. With the so-called London patient, they seem to have succeeded.
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+16 +1
Scientists detect a first new strain of HIV virus in 19 years
For the first time in 19 years, a team of scientists have detected a new strain of HIV. The strain is a part of the Group M version of HIV-1, the same family of virus subtypes to blame for the global HIV pandemic, according to Abbott Laboratories, which conducted the research along with the University of Missouri, Kansas City.
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+2 +1
HIV diagnoses in England fall to lowest level since 2000
Diagnoses of HIV in England have fallen to their lowest level in almost two decades. However, Public Health England (PHE) said challenges around the virus remain, with figures showing that almost half the people newly diagnosed last year were at a late stage of infection, increasing their risk of death. Diagnoses fell by just over a quarter (28%) from 6,271 in 2015 to 4,484 in 2018, PHE said, adding that the continued decline in the virus was down to the success of preventive measures.
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+3 +1
A third person may have become HIV-free after a bone marrow transplant
Following news of a man who has been free of HIV since cancer treatment, a third case has now been reported, adding to evidence it may be possible to cure HIV
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+6 +1
Trial of HIV prevention implant hailed as boost in fight against disease
An implant containing an HIV-prevention drug has been trialled in humans, in a step experts have hailed as an exciting development in curtailing infections. Pre-exposure prophylaxis, or PrEP, with antiretroviral drugs has become a hot topic in recent years, with the drugs shown to substantially reduce the risk of contracting HIV from an HIV-positive partner. PrEP pills are already available through the NHS in Scotland to high-risk individuals, while trials are under way in England.
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+4 +1
For the First Time, Researchers Eliminate HIV From the Genomes of Living Animals
There’s no question that powerful anti-HIV medications can do a fairly good job of keeping the virus under control. Used properly, these anti-retroviral drugs (ARVs) can suppress HIV enough to keep it at levels so low they’re undetectable in the blood, which drastically lowers the chance of spreading the virus during sexual activity or transfusions. But ARVs can only do so much.
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+26 +1
Scientists Reveal Unexpected Outcome of China's Rogue Human Gene Editing Trial
In 2018, the Chinese scientist He Jiankui, Ph.D., altered the DNA of two human embryos, which were born as two healthy twin girls named Lulu and Nana. Against the violent ethical uproar in the medical community, He defended his experiment by claiming that the genetic changes he made were benign — they were meant to promote HIV resistance — but research published Monday in Nature Medicine has revealed that he may have spoken too soon.
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+3 +1
Genetic Mutation that Prevents HIV Infection Tied to Earlier Death
Those with two copies of the delta32 allele in the CCR5 gene are 21 percent more likely to die by age 76, although it's not clear why.
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+16 +1
Gilead to donate HIV prevention drug to 200,000 patients
Gilead Sciences will give free Truvada pills to 200,000 uninsured people for the next 11 years to help prevent new HIV infections, the pharmaceutical company said Thursday. The announcement of the donation came just one day after the company said a generic version of the daily pill would be available in September 2020, a year earlier than expected.
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+24 +1
Scientists Identify Factors That Make People Naturally Resistant to H.I.V.
Developing an H.I.V. vaccine has been a perplexing challenge that has mostly resulted in failure, but now scientists have identified key factors that allow some people to naturally suppress the H.I.V. virus—work that could lead to better vaccines to both treat and prevent the infection. Researchers believe they have identified crucial points on the virus's surface where the immune system can successfully attack H.I.V.
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+6 +1
End to Aids in sight as huge study finds drugs stop HIV transmission
An end to the Aids epidemic could be in sight after a landmark study found men whose HIV infection was fully suppressed by antiretroviral drugs had no chance of infecting their partner. The success of the medicine means that if everyone with HIV were fully treated, there would be no further infections.
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+10 +1
First Ever Living Donor Hiv-To-Hiv Kidney Transplant
For the first time, a person living with HIV has donated a kidney to a transplant recipient also living with HIV. A multidisciplinary team from Johns Hopkins Medicine completed the living donor HIV-to-HIV kidney transplant on Mar. 25. The doctors say both the donor and the recipient are doing well. “This is the first time someone living with HIV has been allowed to donate a kidney, ever, in the world, and that’s huge,” says Dorry Segev, M.D., Ph.D., professor of surgery at the Johns Hopkins University School of Medicine.
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+8 +1
Monthly HIV injection could free patients from gruelling drug regimen
Long-acting medicines have proved as effective as daily pills in preventing HIV from replicating, according to results from twin trials that enrolled more than 1,000 people in 16 countries. The drugs tested, cabotegravir and rilpivirine, are given once a month as an injection. They are the first of several long-acting antiretroviral HIV medicines in development, which researchers hope will tackle one of the toughest challenges in the fight against HIV: how to ensure that people consistently take the drugs that can prevent the virus from replicating in their cells. Skipped doses put people with HIV, and their sexual partners, at risk.
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